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Oral Tolerance to Environmental Mycobacteria Interferes with Intradermal, but Not Pulmonary, Immunization against Tuberculosis

Bacille Calmette–Guérin (BCG) is currently the only approved vaccine against tuberculosis (TB) and is administered in over 150 countries worldwide. Despite its widespread use, the vaccine has a variable protective efficacy of 0–80%, with the lowest efficacy rates in tropical regions where TB is most...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Price, Dominique N., Kusewitt, Donna F., Lino, Christopher A., McBride, Amber A., Muttil, Pavan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859477/
https://ncbi.nlm.nih.gov/pubmed/27153120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005614
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