Integrated Regional Cardiac Hemodynamic Imaging and RNA Sequencing Reveal Corresponding Heterogeneity of Ventricular Wall Shear Stress and Endocardial Transcriptome

BACKGROUND: Unlike arteries, in which regionally distinct hemodynamics are associated with phenotypic heterogeneity, the relationships between endocardial endothelial cell phenotype and intraventricular flow remain largely unexplored. We investigated regional differences in left ventricular wall she...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: McCormick, Margaret E., Manduchi, Elisabetta, Witschey, Walter R. T., Gorman, Robert C., Gorman, Joseph H., Jiang, Yi‐Zhou, Stoeckert, Christian J., Barker, Alex J., Markl, Michael, Davies, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859290/
https://ncbi.nlm.nih.gov/pubmed/27091183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.003170
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