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Transcriptional Profiling of Foam Cells Reveals Induction of Guanylate‐Binding Proteins Following Western Diet Acceleration of Atherosclerosis in the Absence of Global Changes in Inflammation

BACKGROUND: Foam cells are central to two major pathogenic processes in atherogenesis: cholesterol buildup in arteries and inflammation. The main underlying cause of cholesterol deposition in arteries is hypercholesterolemia. This study aimed to assess, in vivo, whether elevated plasma cholesterol a...

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Опубликовано в: :J Am Heart Assoc
Главные авторы: Goo, Young‐Hwa, Son, Se‐Hee, Yechoor, Vijay K., Paul, Antoni
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859273/
https://ncbi.nlm.nih.gov/pubmed/27091181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002663
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