Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations

Human Ataxin-2 (ATXN2) gene locus variants have been associated with obesity, diabetes mellitus type 1,and hypertension in genome-wide association studies, whereas mouse studies showed the knock-out of Atxn2 to lead to obesity, insulin resistance, and dyslipidemia. Intriguingly, the deficiency of AT...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Proteomics
Asıl Yazarlar: Meierhofer, David, Halbach, Melanie, Şen, Nesli Ece, Gispert, Suzana, Auburger, Georg
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858951/
https://ncbi.nlm.nih.gov/pubmed/26850065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.056770
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