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Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation

Exosomes, derived from multivesicular bodies (MVBs), contain proteins and genetic materials from their cell of origin and are secreted from various cells types, including kidney epithelial cells. In general, it is thought that protein cargo is ubiquitylated but that ubiquitin is cleaved by specific...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Cell Proteomics
Main Authors: Huebner, Alyssa R., Cheng, Lei, Somparn, Poorichaya, Knepper, Mark A., Fenton, Robert A., Pisitkun, Trairak
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Biochemistry and Molecular Biology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858939/
https://ncbi.nlm.nih.gov/pubmed/26884507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.054965
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