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In silico lineage tracing through single cell transcriptomics identifies a neural stem cell population in planarians

BACKGROUND: The planarian Schmidtea mediterranea is a master regenerator with a large adult stem cell compartment. The lack of transgenic labeling techniques in this animal has hindered the study of lineage progression and has made understanding the mechanisms of tissue regeneration a challenge. How...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Molinaro, Alyssa M., Pearson, Bret J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858873/
https://ncbi.nlm.nih.gov/pubmed/27150006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0937-9
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