Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway

BACKGROUND: Type-2 diabetics have an increased risk of cardiomyopathy, and heart failure is a major cause of death among these patients. Growing evidence indicates that proinflammatory cytokines may induce the development of insulin resistance, and that anti-inflammatory medications may reverse this...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Korkmaz-Icöz, Sevil, Al Said, Samer, Radovits, Tamás, Li, Shiliang, Brune, Maik, Hegedűs, Péter, Atmanli, Ayhan, Ruppert, Mihály, Brlecic, Paige, Lehmann, Lorenz Heyne, Lahrmann, Bernd, Grabe, Niels, Yoshikawa, Yutaka, Yasui, Hiroyuki, Most, Patrick, Karck, Matthias, Szabó, Gábor
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858866/
https://ncbi.nlm.nih.gov/pubmed/27153943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0383-8
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