σ(2)-Adaptin Facilitates Basal Synaptic Transmission and Is Required for Regenerating Endo-Exo Cycling Pool Under High-Frequency Nerve Stimulation in Drosophila

The functional requirement of adapter protein 2 (AP2) complex in synaptic membrane retrieval by clathrin-mediated endocytosis is not fully understood. Here we isolated and functionally characterized a mutation that dramatically altered synaptic development. Based on the aberrant neuromuscular juncti...

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Vydáno v:Genetics
Hlavní autoři: Choudhury, Saumitra Dey, Mushtaq, Zeeshan, Reddy-Alla, Suneel, Balakrishnan, Sruthi S., Thakur, Rajan S., Krishnan, Kozhalmannom S., Raghu, Padinjat, Ramaswami, Mani, Kumar, Vimlesh
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2016
Témata:
Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858786/
https://ncbi.nlm.nih.gov/pubmed/26920756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.183863
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