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Protein stability: computation, sequence statistics, and new experimental methods
Calculating protein stability and predicting stabilizing mutations remain exceedingly difficult tasks, largely due to the inadequacy of potential functions, the difficulty of modeling entropy and the unfolded state, and challenges of sampling, particularly of backbone conformations. Yet, computation...
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| Publicado no: | Curr Opin Struct Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858314/ https://ncbi.nlm.nih.gov/pubmed/26497286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.09.002 |
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