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Insulin Signaling in Insulin Resistance States and Cancer: A Modeling Analysis

Insulin resistance is the common denominator of several diseases including type 2 diabetes and cancer, and investigating the mechanisms responsible for insulin signaling impairment is of primary importance. A mathematical model of the insulin signaling network (ISN) is proposed and used to investiga...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Bertuzzi, Alessandro, Conte, Federica, Mingrone, Geltrude, Papa, Federico, Salinari, Serenella, Sinisgalli, Carmela
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858213/
https://ncbi.nlm.nih.gov/pubmed/27149630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154415
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