Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

The over-expression of human neuroglobin (NGB), a heme-protein preferentially expressed in the brain, displays anti-apoptotic effects against hypoxic/ischemic and oxidative stresses enhancing neuron survival. As hypoxic and oxidative stress injury frequently occurs in fast proliferating neoplastic t...

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Publicat a:PLoS One
Autors principals: Fiocchetti, Marco, Cipolletti, Manuela, Leone, Stefano, Naldini, Antonella, Carraro, Fabio, Giordano, Daniela, Verde, Cinzia, Ascenzi, Paolo, Marino, Maria
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858147/
https://ncbi.nlm.nih.gov/pubmed/27149623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154959
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