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High expression of podoplanin in squamous cell carcinoma of the tongue occurs predominantly in patients ≤40 years but does not correlate with tumour spread

More than 30% of patients with squamous cell carcinoma (SCC) of the mobile tongue have clinically undetectable lymph node metastasis. Tumour cells can spread as single cells or collectively. A protein known to play a role in both processes is podoplanin, which is expressed in endothelial cells not o...

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Detalhes bibliográficos
Publicado no:J Pathol Clin Res
Main Authors: Sgaramella, Nicola, Lindell Jonsson, Eva, Boldrup, Linda, Califano, Luigi, Coates, Philip J, Tartaro, Gianpaolo, Lo Muzio, Lorenzo, Fåhraeus, Robin, Colella, Giuseppe, Dell'Aversana Orabona, Giovanni, Loljung, Lotta, Santagata, Mario, Rossiello, Riccardo, Wilms, Torben, Danielsson, Karin, Laurell, Göran, Nylander, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858125/
https://ncbi.nlm.nih.gov/pubmed/27499910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.28
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