Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and Thickening

PURPOSE: Plasma kallikrein is a serine protease and circulating component of inflammation, which exerts clinically significant effects on vasogenic edema. This study examines the role of plasma kallikrein in VEGF-induced retinal edema. METHODS: Intravitreal injections of VEGF and saline vehicle were...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Clermont, Allen, Murugesan, Nivetha, Zhou, Qunfang, Kita, Takeshi, Robson, Peter A., Rushbrooke, Louise J., Evans, D. Michael, Aiello, Lloyd Paul, Feener, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857835/
https://ncbi.nlm.nih.gov/pubmed/27138737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18272
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