A Novel [(15)N] Glutamine Flux using LC-MS/MS-SRM for Determination of Nucleosides and Nucleobases

The growth of cancer cells relies more on increased proliferation and autonomy compared to non-malignant cells. The rate of de novo nucleotide biosynthesis correlates with cell proliferation rates. In part, glutamine is needed to sustain high rates of cellular proliferation as a key nitrogen donor i...

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Détails bibliographiques
Publié dans:J Anal Bioanal Tech
Auteurs principaux: Jin, Feng, Bhowmik, Salil Kumar, Putluri, Vasanta, Gu, Franklin, Gohlke, Jie, Von Rundstedt, Friedrich Carl, Dasgupta, Subhamoy, Krishnapuram, Rashmi, O’Malley, Bert W., Sreekumar, Arun, Putluri, Nagireddy
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857768/
https://ncbi.nlm.nih.gov/pubmed/27158554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9872.1000267
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