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Endotoxemia-induced cytokine-mediated responses of hippocampal astrocytes transmitted by cells of the brain–immune interface

Systemic inflammation shifts the brain microenvironment towards a proinflammatory state. However, how peripheral inflammation mediates changes in the brain remains to be clarified. We aimed to identify hippocampal cells and cytokines that respond to endotoxemia. Mice were intraperitoneally injected...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hasegawa-Ishii, Sanae, Inaba, Muneo, Umegaki, Hiroyuki, Unno, Keiko, Wakabayashi, Keiji, Shimada, Atsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857737/
https://ncbi.nlm.nih.gov/pubmed/27149601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25457
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