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Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness

Individual cells within a tumour can exhibit distinct genetic and molecular features. The impact of such diversification on metastatic potential is unknown. Here we identify clonal human breast cancer subpopulations that display different levels of morphological and molecular diversity. Highly varia...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Nguyen, Alexander, Yoshida, Mitsukuni, Goodarzi, Hani, Tavazoie, Sohail F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857405/
https://ncbi.nlm.nih.gov/pubmed/27138336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11246
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