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ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive neoplastic diseases, associated with a remarkably poor prognosis. However, the molecular mechanisms underlying the development of PDAC remain elusive. The aim of this study was to identify genes whose expressions are c...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Fukushima, Hiroto, Yasumoto, Makiko, Ogasawara, Sachiko, Akiba, Jun, Kitasato, Yuhei, Nakayama, Masamichi, Naito, Yoshiki, Ishida, Yusuke, Okabe, Yoshinobu, Yasunaga, Masafumi, Horiuchi, Hiroyuki, Sakamoto, Etsuko, Itadani, Hiraku, Mizuarai, Shinji, Oie, Shinji, Yano, Hirohisa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857279/
https://ncbi.nlm.nih.gov/pubmed/27145964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0516-4
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