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Lactation undernutrition leads to multigenerational molecular programming of hypothalamic gene networks controlling reproduction

BACKGROUND: Reproductive success is dependent on development of hypothalamic circuits involving many hormonal systems working in concert to regulate gonadal function and sexual behavior. The timing of pubertal initiation and progression in mammals is likely influenced by the nutritional and metaboli...

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Vydáno v:BMC Genomics
Hlavní autoři: Kaczmarek, Monika M., Mendoza, Tamra, Kozak, Leslie P.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857247/
https://ncbi.nlm.nih.gov/pubmed/27146259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2615-4
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