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Nicotine Metabolism in Young Adult Daily Menthol and Nonmenthol Smokers

INTRODUCTION: Menthol cigarette smoking may increase the risk for tobacco smoke exposure and inhibit nicotine metabolism in the liver. Nicotine metabolism is primarily mediated by the enzyme CYP2A6 and the nicotine metabolite ratio (NMR = trans 3′ hydroxycotinine/cotinine) is a phenotypic proxy for...

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Detalhes bibliográficos
Publicado no:Nicotine Tob Res
Main Authors: Fagan, Pebbles, Pokhrel, Pallav, Herzog, Thaddeus A., Pagano, Ian S., Franke, Adrian A., Clanton, Mark S., Alexander, Linda A., Trinidad, Dennis R., Sakuma, Kari-Lyn K., Johnson, Carl A., Moolchan, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857147/
https://ncbi.nlm.nih.gov/pubmed/25995160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntv109
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