Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer’s disease

Prior studies have identified white matter abnormalities in Alzheimer’s disease (AD). Yet, cross-sectional studies in normal older individuals show little evidence for an association between markers of AD risk (APOE4 genotype and amyloid deposition), and white matter integrity. Here, 108 normal olde...

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Publicado en:Neurobiol Aging
Autores principales: Rieckmann, Anna, Van Dijk, Koene RA, Sperling, Reisa A, Johnson, Keith A, Buckner, Randy L, Hedden, Trey
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857135/
https://ncbi.nlm.nih.gov/pubmed/27143434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.03.016
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