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Mechanistic and quantitative insight into cell surface targeted molecular imaging agent design

Molecular imaging agent design involves simultaneously optimizing multiple probe properties. While several desired characteristics are straightforward, including high affinity and low non-specific background signal, in practice there are quantitative trade-offs between these properties. These includ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Liang, Bhatnagar, Sumit, Deschenes, Emily, Thurber, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857130/
https://ncbi.nlm.nih.gov/pubmed/27147293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25424
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