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Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2

Polycomb group (PcG) proteins are transcriptional repressors of numerous genes, many of which regulate cell cycle progression or developmental processes. We used zebrafish to study Enhancer of zeste homolog 2 (Ezh2), the PcG protein responsible for placing the transcriptional repressive H3K27me3 mar...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: San, Bilge, Chrispijn, Naomi D., Wittkopp, Nadine, van Heeringen, Simon J., Lagendijk, Anne K., Aben, Marco, Bakkers, Jeroen, Ketting, René F., Kamminga, Leonie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857124/
https://ncbi.nlm.nih.gov/pubmed/27145952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24658
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