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Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes

Infection by Group A Streptococcus pyogenes (GAS) is a leading cause of severe invasive disease in humans, including streptococcal toxic shock syndrome and necrotizing fasciitis. GAS infections lead to nearly 163,000 annual deaths worldwide. Hypervirulent strains of S. pyogenes have evolved a pletho...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Moon, Andrea F., Krahn, Juno M., Lu, Xun, Cuneo, Matthew J., Pedersen, Lars C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856990/
https://ncbi.nlm.nih.gov/pubmed/26969731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw143
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