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The downregulation of the RNA-binding protein Staufen2 in response to DNA damage promotes apoptosis

Staufen2 (Stau2) is an RNA-binding protein involved in cell fate decision by controlling several facets of mRNA processing including localization, splicing, translation and stability. Herein we report that exposure to DNA-damaging agents that generate replicative stress such as camptothecin (CPT), 5...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Zhang, Xin, Trépanier, Véronique, Beaujois, Remy, Viranaicken, Wildriss, Drobetsky, Elliot, DesGroseillers, Luc
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856980/
https://ncbi.nlm.nih.gov/pubmed/26843428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw057
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