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The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer

CD44 is a cell surface HA-binding glycoprotein that is overexpressed to some extent by almost all tumors of epithelial origin and plays an important role in tumor initiation and metastasis. CD44 is a compelling marker for cancer stem cells of many solid malignancies. In addition, interaction of HA a...

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Библиографические подробности
Опубликовано в: :Stem Cells Int
Главные авторы: Thapa, Ranjeeta, Wilson, George D.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856920/
https://ncbi.nlm.nih.gov/pubmed/27200096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2087204
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