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Integration of Structural Dynamics and Molecular Evolution via Protein Interaction Networks: A New Era in Genomic Medicine

Sequencing technologies are revealing many new non-synonymous single nucleotide variants (nsSNVs) in each personal exome. To assess their functional impacts, comparative genomics is frequently employed to predict if they are benign or not. However, evolutionary analysis alone is insufficient, becaus...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Curr Opin Struct Biol
मुख्य लेखकों: Kumar, Avishek, Butler, Brandon M., Kumar, Sudhir, Ozkan, S. Banu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856467/
https://ncbi.nlm.nih.gov/pubmed/26684487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.11.002
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