Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer

E-cadherin is a central molecule in the process of gastric carcinogenesis and its posttranslational modifications by N-glycosylation have been described to induce a deleterious effect on cell adhesion associated with tumor cell invasion. However, the role that site-specific glycosylation of E-cadher...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Carvalho, S, Catarino, TA, Dias, AM, Kato, M, Almeida, A, Hessling, B, Figueiredo, J, Gärtner, F, Sanches, JM, Ruppert, T, Miyoshi, E, Pierce, M, Carneiro, F, Kolarich, D, Seruca, R, Yamaguchi, Y, Taniguchi, N, Reis, CA, Pinho, SS
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856288/
https://ncbi.nlm.nih.gov/pubmed/26189796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.225
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