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A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection

Immune cells, including natural killer (NK) cells, recognize transformed cells and eliminate them in a process termed immunosurveillance. It is thought that tumor cells evade immunosurveillance by shedding membrane ligands that bind to the NKG2D activating receptor on NK cells and/or T cells, and de...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Deng, Weiwen, Gowen, Benjamin G., Zhang, Li, Wang, Lin, Lau, Stephanie, Iannello, Alexandre, Xu, Jianfeng, Rovis, Tihana L., Xiong, Na, Raulet, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856222/
https://ncbi.nlm.nih.gov/pubmed/25745066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1258867
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