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AMPKα(1) knockout enhances nociceptive behaviors and spinal glutamatergic synaptic activities via production of reactive oxygen species in the spinal dorsal horn

Emerging studies have shown that pharmacological activation of AMPK produces potent analgesic effects in different animal pain models. Currently, the spinal molecular and synaptic mechanism by which AMPK regulates the pain signaling system remains unclear. To address this issue, we utilized the Cre-...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Maixner, Dylan W., Yan, Xisheng, Hooks, Shelley B., Weng, Han-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856024/
https://ncbi.nlm.nih.gov/pubmed/27058143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.03.061
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