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An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies
BACKGROUND: Many different methods exist to adjust for variability in cell-type mixture proportions when analyzing DNA methylation studies. Here we present the result of an extensive simulation study, built on cell-separated DNA methylation profiles from Illumina Infinium 450K methylation data, to c...
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| Udgivet i: | Genome Biol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855979/ https://ncbi.nlm.nih.gov/pubmed/27142380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0935-y |
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