Trigger factor assisted soluble expression of recombinant spike protein of porcine epidemic diarrhea virus in Escherichia coli

BACKGROUND: Porcine epidemic diarrhea virus (PEDV) is a highly contagious enteric pathogen of swine. The spike glycoprotein (S) of PEDV is the major immunogenic determinant that plays a pivotal role in the induction of neutralizing antibodies against PEDV, which therefore is an ideal target for the...

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Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Piao, Da-Chuan, Shin, Do-Woon, Kim, In-Seon, Li, Hui-Shan, Oh, Seo-Ho, Singh, Bijay, Maharjan, S., Lee, Yoon-Seok, Bok, Jin-Duck, Cho, Chong-Su, Hong, Zhong-Shan, Kang, Sang-Kee, Choi, Yun-Jaie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855837/
https://ncbi.nlm.nih.gov/pubmed/27142206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-016-0268-7
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