Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy

Inherited demyelinating peripheral neuropathies are progressive incurable diseases without effective treatment. To develop a gene therapy approach targeting myelinating Schwann cells that can be translatable, we delivered a lentiviral vector using a single lumbar intrathecal injection and a myelin-s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kagiava, Alexia, Sargiannidou, Irene, Theophilidis, George, Karaiskos, Christos, Richter, Jan, Bashiardes, Stavros, Schiza, Natasa, Nearchou, Marianna, Christodoulou, Christina, Scherer, Steven S., Kleopa, Kleopas A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855595/
https://ncbi.nlm.nih.gov/pubmed/27035961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522202113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados