Stress-induced gene expression and behavior are controlled by DNA methylation and methyl donor availability in the dentate gyrus

Stressful events evoke long-term changes in behavioral responses; however, the underlying mechanisms in the brain are not well understood. Previous work has shown that epigenetic changes and immediate-early gene (IEG) induction in stress-activated dentate gyrus (DG) granule neurons play a crucial ro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Saunderson, Emily A., Spiers, Helen, Mifsud, Karen R., Gutierrez-Mecinas, Maria, Trollope, Alexandra F., Shaikh, Abeera, Mill, Jonathan, Reul, Johannes M. H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855538/
https://ncbi.nlm.nih.gov/pubmed/27078100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524857113
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