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Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood. Here we describe a role for asparagine as an amino acid exchange factor: intracellular asparagine exchanges with extracellular am...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855534/ https://ncbi.nlm.nih.gov/pubmed/27126896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11457 |
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