Vaccinia vaccine–based immunotherapy arrests and reverses established pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease without any cure. Both human disease and animal models demonstrate dysregulated wound healing and unregulated fibrogenesis in a background of low-grade chronic T lymphocyte infiltration. Tissue-resident memory T cells (Trm) are emerging as impor...

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Udgivet i:JCI Insight
Main Authors: Collins, Samuel L., Chan-Li, Yee, Oh, MinHee, Vigeland, Christine L., Limjunyawong, Nathachit, Mitzner, Wayne, Powell, Jonathan D., Horton, Maureen R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855513/
https://ncbi.nlm.nih.gov/pubmed/27158671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.83116
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