Time-differentiated target temperature management after out-of-hospital cardiac arrest: a multicentre, randomised, parallel-group, assessor-blinded clinical trial (the TTH48 trial): study protocol for a randomised controlled trial

BACKGROUND: The application of therapeutic hypothermia (TH) for 12 to 24 hours following out-of-hospital cardiac arrest (OHCA) has been associated with decreased mortality and improved neurological function. However, the optimal duration of cooling is not known. We aimed to investigate whether targe...

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Publicat a:Trials
Autors principals: Kirkegaard, Hans, Rasmussen, Bodil S, de Haas, Inge, Nielsen, Jørgen Feldbæk, Ilkjær, Susanne, Kaltoft, Anne, Jeppesen, Anni Nørregaard, Grejs, Anders, Duez, Christophe Henri Valdemar, Larsen, Alf Inge, Pettilä, Ville, Toome, Valdo, Arus, Urmet, Taccone, Fabio Silvio, Storm, Christian, Skrifvars, Markus B., Søreide, Eldar
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855491/
https://ncbi.nlm.nih.gov/pubmed/27142588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1338-9
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