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High Throughput Screening for Drugs that Modulate Intermediate Filament Proteins

Intermediate filament (IF) proteins have unique and complex cell and tissue distribution. Importantly, IF gene mutations cause or predispose to more than 80 human tissue-specific diseases (IF-pathies), with the most severe disease phenotypes being due to mutations at conserved residues that result i...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Sun, Jingyuan, Groppi, Vincent E., Gui, Honglian, Chen, Lu, Xie, Qing, Liu, Li, Omary, M. Bishr
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855291/
https://ncbi.nlm.nih.gov/pubmed/26795471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.09.029
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