Matrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression

The mechanical environment is crucial for intervertebral disc degeneration (IDD). However, the mechanisms underlying the regulation of cartilage endplate (CEP) calcification by altered matrix stiffness remain unclear. In this study, we found that matrix stiffness of CEP was positively correlated wit...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Ming-Han, Sun, Chao, Yao, Yuan, Fan, Xin, Liu, Huan, Cui, You-Hong, Bian, Xiu-Wu, Huang, Bo, Zhou, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855171/
https://ncbi.nlm.nih.gov/pubmed/27142968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25401
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