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Matrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression

The mechanical environment is crucial for intervertebral disc degeneration (IDD). However, the mechanisms underlying the regulation of cartilage endplate (CEP) calcification by altered matrix stiffness remain unclear. In this study, we found that matrix stiffness of CEP was positively correlated wit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Liu, Ming-Han, Sun, Chao, Yao, Yuan, Fan, Xin, Liu, Huan, Cui, You-Hong, Bian, Xiu-Wu, Huang, Bo, Zhou, Yue
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855171/
https://ncbi.nlm.nih.gov/pubmed/27142968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25401
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