Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome

Glucocorticoids are the primary therapy for nephrotic syndrome (NS), but have serious side effects and are ineffective in ~20–50% of patients. Thiazolidinediones have recently been suggested to be renoprotective, and to modulate podocyte glucocorticoid-mediated nuclear receptor signaling. We hypothe...

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Udgivet i:Sci Rep
Main Authors: Agrawal, S., Chanley, M. A., Westbrook, D., Nie, X., Kitao, T., Guess, A. J., Benndorf, R., Hidalgo, G., Smoyer, W. E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855145/
https://ncbi.nlm.nih.gov/pubmed/27142691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24392
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