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17β‐estradiol ameliorates age‐associated loss of fibroblast function by attenuating IFN‐γ/STAT1‐dependent miR‐7 upregulation

Age‐related defects in fibroblast differentiation and functionality were previously shown to be associated with impaired hyaluronan (HA) synthase 2 (HAS2) and epidermal growth factor receptor (EGFR) function, as a result of upregulated microRNA‐7 (miR‐7) expression. In aging fibroblasts, inhibiting...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Midgley, Adam C., Morris, Glyn, Phillips, Aled O., Steadman, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854905/
https://ncbi.nlm.nih.gov/pubmed/26931423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12462
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