Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production

Circulating levels of fibroblast growth factor 23 (FGF23) are elevated in patients with chronic kidney disease (CKD), but the mechanisms are poorly understood. Here we tested whether inflammation and iron deficiency regulate FGF23. In wild-type mice, acute inflammation induced by single injections o...

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Bibliographic Details
Published in:Kidney Int
Main Authors: David, Valentin, Martin, Aline, Isakova, Tamara, Spaulding, Christina, Qi, Lixin, Ramirez, Veronica, Zumbrennen-Bullough, Kimberly B., Sun, Chia Chi, Lin, Herbert Y., Babitt, Jodie L., Wolf, Myles
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854810/
https://ncbi.nlm.nih.gov/pubmed/26535997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.290
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