Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production

Circulating levels of fibroblast growth factor 23 (FGF23) are elevated in patients with chronic kidney disease (CKD), but the mechanisms are poorly understood. Here we tested whether inflammation and iron deficiency regulate FGF23. In wild-type mice, acute inflammation induced by single injections o...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: David, Valentin, Martin, Aline, Isakova, Tamara, Spaulding, Christina, Qi, Lixin, Ramirez, Veronica, Zumbrennen-Bullough, Kimberly B., Sun, Chia Chi, Lin, Herbert Y., Babitt, Jodie L., Wolf, Myles
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854810/
https://ncbi.nlm.nih.gov/pubmed/26535997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.290
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