Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production

Circulating levels of fibroblast growth factor 23 (FGF23) are elevated in patients with chronic kidney disease (CKD), but the mechanisms are poorly understood. Here we tested whether inflammation and iron deficiency regulate FGF23. In wild-type mice, acute inflammation induced by single injections o...

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Bibliografske podrobnosti
izdano v:Kidney Int
Main Authors: David, Valentin, Martin, Aline, Isakova, Tamara, Spaulding, Christina, Qi, Lixin, Ramirez, Veronica, Zumbrennen-Bullough, Kimberly B., Sun, Chia Chi, Lin, Herbert Y., Babitt, Jodie L., Wolf, Myles
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854810/
https://ncbi.nlm.nih.gov/pubmed/26535997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.290
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