Lamotrigine use in pregnancy and risk of orofacial cleft and other congenital anomalies

OBJECTIVE: To test previous signals of a risk of orofacial cleft (OC) and clubfoot with exposure to the antiepileptic lamotrigine, and to investigate risk of other congenital anomalies (CA). METHODS: This was a population-based case–malformed control study based on 21 EUROCAT CA registries covering...

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Publicado en:Neurology
Autores principales: Dolk, Helen, Wang, Hao, Loane, Maria, Morris, Joan, Garne, Ester, Addor, Marie-Claude, Arriola, Larraitz, Bakker, Marian, Barisic, Ingeborg, Doray, Berenice, Gatt, Miriam, Kallen, Karin, Khoshnood, Babak, Klungsoyr, Kari, Lahesmaa-Korpinen, Anna-Maria, Latos-Bielenska, Anna, Mejnartowicz, Jan P., Nelen, Vera, Neville, Amanda, O'Mahony, Mary, Pierini, Anna, Rißmann, Anke, Tucker, David, Wellesley, Diana, Wiesel, Awi, de Jong-van den Berg, Lolkje T.W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854591/
https://ncbi.nlm.nih.gov/pubmed/27053714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002540
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