Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia

RATIONALE: Perioperative myocardial ischemia is common in high-risk patients. The use of interventional revascularisation or even thrombolysis is limited in this patient subset due to exceedingly high bleeding risks. Blockade of voltage-gated sodium channels (VGSC) with lidocaine had been suggested...

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Veröffentlicht in:PLoS One
Hauptverfasser: Müller-Edenborn, Björn, Kania, Gabriela, Osto, Elena, Jakob, Philipp, Krasniqi, Nazmi, Beck-Schimmer, Beatrice, Blyszczuk, Przemyslaw, Eriksson, Urs
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854463/
https://ncbi.nlm.nih.gov/pubmed/27140425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154699
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