GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice

BACKGROUND: Beige adipocytes comprise a unique thermogenic cell type in the white adipose tissue (WAT) of rodents and humans, and play a critical role in energy homeostasis. In this scenario, recruitment of beige cells has been an important focus of interest for the development of novel therapeutic...

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Publicat a:PLoS One
Autors principals: Coelho, Michella S., de Lima, Caroline L., Royer, Carine, Silva, Janaina B., Oliveira, Fernanda C. B., Christ, Camila G., Pereira, Sidney A., Bao, Sonia N., Lima, Maria C. A., Pitta, Marina G. R., Pitta, Ivan R., Neves, Francisco A. R., Amato, Angélica A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854408/
https://ncbi.nlm.nih.gov/pubmed/27138164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154310
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