Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin

APOL1, a secreted high-density lipoprotein, is expressed in different human tissues. Genetic variants of APOL1 are described to be associated with the development of end stage renal diseases in African Americans. In human kidney, APOL1 is mainly expressed in podocytes that are responsible for proper...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kotb, Ahmed M., Simon, Ole, Blumenthal, Antje, Vogelgesang, Silke, Dombrowski, Frank, Amann, Kerstin, Zimmermann, Uwe, Endlich, Karlhans, Endlich, Nicole
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854397/
https://ncbi.nlm.nih.gov/pubmed/27138898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153768
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