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Effect of folate status and methylenetetrahydrofolate reductase genotypes on the complications and outcome of high dose methotrexate chemotherapy in north Indian children with acute lymphoblastic leukemia

PURPOSE: The genes of the folate metabolic pathway have been associated with toxicities during high dose methotrexate therapy for childhood ALL, however, the importance of intrinsic folate status in this regard is unclear. METHODS: In the present study the effect of precourse folate levels and MTHFR...

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Detalhes bibliográficos
Publicado no:Indian J Med Paediatr Oncol
Main Authors: Moulik, Nirmalya Roy, Kumar, Archana, Agrawal, Suraksha, Mahdi, Abbas Ali, Kumar, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854052/
https://ncbi.nlm.nih.gov/pubmed/27168705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5851.180144
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