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Assessment of high resolution melt analysis feasibility for evaluation of beta-globin gene mutations as a reproducible, cost-efficient and fast alternative to the present conventional method

BACKGROUND: Beta-thalassemia is the most prevalent monogenic disease throughout the world. It was the first genetic disorder nominated for nation-wide prevention programs involving population screening for heterozygotes and prenatal diagnosis (PND) in Iran. Due to the high prevalence of beta-thalass...

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Detalhes bibliográficos
Publicado no:Adv Biomed Res
Main Authors: Ramezanzadeh, Mahboubeh, Salehi, Mansour, Salehi, Rasoul
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854030/
https://ncbi.nlm.nih.gov/pubmed/27169102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2277-9175.180640
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