Marker genes that are less conserved in their sequences are useful for predicting genome-wide similarity levels between closely related prokaryotic strains

BACKGROUND: The 16s rRNA gene is so far the most widely used marker for taxonomical classification and separation of prokaryotes. Since it is universally conserved among prokaryotes, it is possible to use this gene to classify a broad range of prokaryotic organisms. At the same time, it has often be...

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Publicado no:Microbiome
Main Authors: Lan, Yemin, Rosen, Gail, Hershberg, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853863/
https://ncbi.nlm.nih.gov/pubmed/27138046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-016-0162-5
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https://ncbi.nlm.nih.gov/pmc/articles/PMC4853863/
https://ncbi.nlm.nih.gov/pubmed/27138046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-016-0162-5