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Combined sodium ion sensitivity in agonist binding and internalization of vasopressin V1b receptors

Reducing Na(+) in the extracellular environment may lead to two beneficial effects for increasing agonist binding to cell surface G-protein coupled receptors (GPCRs): reduction of Na(+)-mediated binding block and reduce of receptor internalization. However, such combined effects have not been explor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Koshimizu, Taka-aki, Kashiwazaki, Aki, Taniguchi, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853784/
https://ncbi.nlm.nih.gov/pubmed/27138239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25327
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